What Causes a Fatty Liver: 4 Ways to Fix

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Fatty Liver Disease Causes: 4 Ways to Fix It- Thomas DeLauer…
What is Fatty Liver Disease? Nonalcoholic fatty liver disease (NAFLD) is a term used for a wide range of liver conditions that can affect people who drink very little to no alcohol. Fatty liver can also occur from excess alcohol consumption, but here we will concentrate on NAFLD. NAFLD occurs when an excess buildup of fat in the liver occurs, known as steatosis. Once fat exceeds 5-10% of the liver’s weight, the liver is considered to be a fatty liver. This occurs when the rate of de novo fatty acid synthesis and hepatic fatty acid uptake from plasma is greater than the rate of fatty acid oxidation and export – ie, too much fat is being created and not enough is being metabolized. Liver inflammation is characteristic is nonalcoholic steatohepatitis, one of the more advanced forms of the disease, that can eventually lead to scarring. This damage to the liver is similar to that caused by heavy alcohol use and can progress to liver cancer and cirrhosis (3).

Causes: The exact cause isn’t known, however NAFLD is most common among those in their 40s and 50s who have metabolic syndrome, a cluster of risk factors that raise your chances of a wide range of diseases, including cardiovascular disease and type-2 diabetes. (1)

Metabolic syndrome includes the following risk factors (2):
Midsection fat accumulation
High triglyceride level
Low HDL cholesterol level
High blood pressure
High fasting blood sugar levels

The majority of these risk factors are tied to obesity, so helping to lose weight and maintain a healthy weight is crucial.

What Can You do to Combat Fatty Liver Disease? Currently there are no definitive treatments for fatty liver disease, so treatment is focused on lifestyle changes (3).

1. Cut out drinking

2. Cut out the fruit!

Fructose is absorbed via portal vein and delivered to the liver in much higher concentrations as compared to other tissues. Fructose increases protein levels of all DNL enzymes during its conversion into triglycerides. Additionally, fructose supports lipogenesis in the setting of insulin resistance as fructose does not require insulin for its metabolism, and it directly stimulates SREBP1c, a major transcriptional regulator of DNL

De-Novo lipogenesis

3. Boost Glutathione Levels- Glutathione is needed in order to recover from a fatty liver. Eat things like eggs, cabbage, broccoli and garlic as they have a higher sulfur content which can help convert into Acetyl Cysteine and create more glutathione in the body.

4. Turmeric- Turmeric is a spice whose use as medicine date back thousands of years in Ayurvedic medicine. Curcuminoids are the compounds in turmeric that give the distinct yellow color and are largely credited with the impressive therapeutic benefits of turmeric. Turmeric is both a powerful anti-inflammatory and antioxidant spice, and it is likely these aspects of turmeric that make it especially helpful for those with NAFLD.

Study (7) A randomized double-blind placebo controlled trial took patients suffering from NAFLD and broke them into two groups. One group took 70-mg curcumin once daily for 8 weeks while the other group did the same with a placebo. Multiple measures were taken at baseline and then following the 8 weeks of treatment. It was found that those in the curcumin group experienced a significant reduction in liver fat content when compared to the placebo group – on average the curcumin participants experienced a 78.9% improvement in liver fat content! Additional significant reductions occurred in body mass index, serum total cholesterol levels, LDL cholesterol, triglycerides, and blood glucose when compared to the placebo group.

References:
1. Nonalcoholic fatty liver disease

2. What is metabolic syndrome

3. Vitamin E and Non-alcoholic Fatty Liver Disease

4. Reactive oxygen species

5. Obesity and nonalcoholic fatty liver disease: biochemical, metabolic, and clinical implications

6. The total antioxidant content of more than 3100 foods, beverages, spices, herbs and supplements used worldwide

7. Treatment of non-alcoholic fatty liver disease with curcumin: a randomized placebo-controlled trial

8. Role of Dietary Fructose and Hepatic De Novo Lipogenesis in Fatty Liver Disease. – PubMed – NCBI. (n.d.). Retrieved from

What Causes a Fatty Liver: 4 Ways to Fix

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Fatty Liver Disease Causes: 4 Ways to Fix It- Thomas DeLauer…
What is Fatty Liver Disease? Nonalcoholic fatty liver disease (NAFLD) is a term used for a wide range of liver conditions that can affect people who drink very little to no alcohol. Fatty liver can also occur from excess alcohol consumption, but here we will concentrate on NAFLD. NAFLD occurs when an excess buildup of fat in the liver occurs, known as steatosis. Once fat exceeds 5-10% of the liver’s weight, the liver is considered to be a fatty liver. This occurs when the rate of de novo fatty acid synthesis and hepatic fatty acid uptake from plasma is greater than the rate of fatty acid oxidation and export - ie, too much fat is being created and not enough is being metabolized. Liver inflammation is characteristic is nonalcoholic steatohepatitis, one of the more advanced forms of the disease, that can eventually lead to scarring. This damage to the liver is similar to that caused by heavy alcohol use and can progress to liver cancer and cirrhosis (3).

Causes: The exact cause isn’t known, however NAFLD is most common among those in their 40s and 50s who have metabolic syndrome, a cluster of risk factors that raise your chances of a wide range of diseases, including cardiovascular disease and type-2 diabetes. (1)

Metabolic syndrome includes the following risk factors (2):
Midsection fat accumulation
High triglyceride level
Low HDL cholesterol level
High blood pressure
High fasting blood sugar levels

The majority of these risk factors are tied to obesity, so helping to lose weight and maintain a healthy weight is crucial.

What Can You do to Combat Fatty Liver Disease? Currently there are no definitive treatments for fatty liver disease, so treatment is focused on lifestyle changes (3).

1. Cut out drinking

2. Cut out the fruit!

Fructose is absorbed via portal vein and delivered to the liver in much higher concentrations as compared to other tissues. Fructose increases protein levels of all DNL enzymes during its conversion into triglycerides. Additionally, fructose supports lipogenesis in the setting of insulin resistance as fructose does not require insulin for its metabolism, and it directly stimulates SREBP1c, a major transcriptional regulator of DNL

De-Novo lipogenesis

3. Boost Glutathione Levels- Glutathione is needed in order to recover from a fatty liver. Eat things like eggs, cabbage, broccoli and garlic as they have a higher sulfur content which can help convert into Acetyl Cysteine and create more glutathione in the body.

4. Turmeric- Turmeric is a spice whose use as medicine date back thousands of years in Ayurvedic medicine. Curcuminoids are the compounds in turmeric that give the distinct yellow color and are largely credited with the impressive therapeutic benefits of turmeric. Turmeric is both a powerful anti-inflammatory and antioxidant spice, and it is likely these aspects of turmeric that make it especially helpful for those with NAFLD.

Study (7) A randomized double-blind placebo controlled trial took patients suffering from NAFLD and broke them into two groups. One group took 70-mg curcumin once daily for 8 weeks while the other group did the same with a placebo. Multiple measures were taken at baseline and then following the 8 weeks of treatment. It was found that those in the curcumin group experienced a significant reduction in liver fat content when compared to the placebo group - on average the curcumin participants experienced a 78.9% improvement in liver fat content! Additional significant reductions occurred in body mass index, serum total cholesterol levels, LDL cholesterol, triglycerides, and blood glucose when compared to the placebo group.

References:
1. Nonalcoholic fatty liver disease
http://www.mayoclinic.org/diseases-conditions/nonalcoholic-fatty-liver-disease/symptoms-causes/syc-20354567

2. What is metabolic syndrome
https://www.nhlbi.nih.gov/health/health-topics/topics/ms

3. Vitamin E and Non-alcoholic Fatty Liver Disease
https://www.nhlbi.nih.gov/health/health-topics/topics/ms

4. Reactive oxygen species
https://www.cancer.gov/publications/dictionaries/cancer-terms?cdrid=687227

5. Obesity and nonalcoholic fatty liver disease: biochemical, metabolic, and clinical implications
https://www.ncbi.nlm.nih.gov/pubmed/20041406

6. The total antioxidant content of more than 3100 foods, beverages, spices, herbs and supplements used worldwide
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841576/

7. Treatment of non-alcoholic fatty liver disease with curcumin: a randomized placebo-controlled trial
https://www.ncbi.nlm.nih.gov/pubmed/27270872

8. Role of Dietary Fructose and Hepatic De Novo Lipogenesis in Fatty Liver Disease. - PubMed - NCBI. (n.d.). Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/26856717

What Causes A Fatty Liver: 4 Ways To Fix
What Causes A Fatty Liver: 4 Ways To Fix
What Causes A Fatty Liver: 4 Ways To Fix
What Causes A Fatty Liver: 4 Ways To Fix
What Causes A Fatty Liver: 4 Ways To Fix

What Causes A Fatty Liver: 4 Ways To Fix

What Causes A Fatty Liver: 4 Ways To Fix

63 Comments


  1. // Reply

    Another great video man! Keep it up!


    1. // Reply

      Cheers for this, I’ve been looking for “what causes the liver to swell” for a while now, and I think this has helped. You ever tried – Bachalaswin Better Body Rule – (Have a quick look on google cant remember the place now ) ? Ive heard some decent things about it and my buddy got cool results with it.


    2. // Reply

      Cheers for this, been searching for “fatty liver and cirrhosis” for a while now, and I think this has helped. Have you ever come across – Bachalaswin Better Body Rule – (do a search on google ) ? Ive heard some unbelievable things about it and my neighbour got great success with it.


    3. // Reply

      He would look better with less muscle.


    4. // Reply

      Winner of a video, I have been researching “best diet for fatty liver” for a while now, and I think this has helped. Have you ever come across – Jeyebastian Venlena Blaster – (should be on google have a look ) ? Ive heard some interesting things about it and my friend got great results with it.


    5. // Reply

      Winner of a video, I been tryin to find out about “how to reverse fatty liver diet” for a while now, and I think this has helped. Ever heard of – Jeyebastian Venlena Blaster – (do a google search ) ? Ive heard some awesome things about it and my partner got cool success with it.


  2. // Reply

    That was spot on and easy to digest! Pun intended!


  3. // Reply

    I like the way Thomas breaks down all the information and makes it easy to understand like those subjects about metabolism it is super hard to understand….


    1. // Reply

      Anthony Aaron A i completely agree 😁👍


    2. // Reply

      Anthony Aaron A I don’t understand your point? Are you watching him for health tips or for entertainment? Regardless he should not spread misinformation


    3. // Reply

      Jason P I don’t understand your point any more….all you do is to attack… Not good 😌


    4. // Reply

      This was great, I’ve been looking for “fatty liver” for a while now, and I think this has helped. Ever heard of – Jeyebastian Venlena Blaster – (should be on google have a look ) ? Ive heard some interesting things about it and my mate got amazing success with it.


  4. // Reply

    Thanks Thomas , I knew only about curcumin ‘s ability to fight cancer but not about its usefulness in improving a fatty liver .


  5. // Reply

    I haven’t had fruit or alcohol for 3 years…don’t need it, don’t miss it.


    1. // Reply

      I ate fruit like a monkey….like literally ate 5 bananas a day, followed by melons, mangos just so I stopped being hungry. Well, I did lose weight but 3 years in I got a FATTY LIVER! 🙁


    2. // Reply

      How is not having any fruit for 3 years a good thing? Lol


    3. // Reply

      +Thordur Hogna
      I know right!! If I don’t eat fruit then I’m craving the really bad stuff like ice cream, sweet baked goods, & lots and lots of candy. Fruit keeps my sweet tooth satisfy and away from the stuff that’s really bad for you. Of course I have it in moderation anyone would get sick with 5 bananas a day like a another person said .


    4. // Reply

      SheepAmongGoats Body obviously does need carbs if ketosis fucks up your sleep so your completely wrong


  6. // Reply

    It’s not carbs in general, it’s fast frucrose from sugar corn sirup and fruit juices.
    Just look up Dr Robert Lustig.


  7. // Reply

    Man I thought I was doing good by eating a lot of fruits for my fatty liver. I’m glad I watched this video because I would have done more harm. I know some fruits are good and have less sugar. Can you please make a video on witch fruits to avoid and which to consume if that’s possible. For example, lemon & limes, grapefruit, blackberries are good because of antioxidants.


    1. // Reply

      FuFill Your ViBes none of them. You should avoid no fruits. Fruits are designed to be digested without issue, avoid processed sugar but if you want to be health, don’t listen to this video.


    2. // Reply

      My doctors says Avoid or cutback on fruits with high sugar…like grapes and tangerines, oranges, bananas….berries are great tho….all the berries…. Kiwi too.


    3. // Reply

      Avacodos, lemons, and all types of berries. Those fruits are all good for you. Limit the high sugar content ones


  8. // Reply

    Take N Acetyl Cysteine if you have a fatty liver… This has been proven to reverse end stage liver failure. NAC is the pre cursor to glutathione.


    1. // Reply

      Anthony Indovina Alpha lipoic acid also.


    2. // Reply

      Anthony Indovina I’m so happy to know this. Thanks for sharing. NAC is a powerful supplement for women with PCOS. incidentally a Keto and IF diet work wonders for PCOS too


  9. // Reply

    Notice how keto fixes almost everything?


    1. // Reply

      Cherie Ambrose are you on the keto diet?


  10. // Reply

    Thomas, have you considered doing one video to speak out against the barbaric cruelty that occurs in factory farms every day?
    Things such as castrating baby male pigs without painkiller or anesthesia, just days after being born, are standard practice in US slaughterhouses…. We, and the animals, could really use an impactful figure such as yourself to do just one video speaking out about these atrocities. There is an animal holocaust going on, 65 billion farm animals slaughtered every year for us, when the scientific arguments that try to affirm that we need to consume meat and dairy are very very weak, and can only cling to vitamin b12 – which yes, we need and is only found in meat BUT it’s actually the product of a bacteria which is on meat and not non-meat foods – we can create this bacteria without involving animals in any way.
    Digressions aside,,, we, and the animals, could use a voice like yours to speak out against this heinous animal cruelty that ends up on most people’s dinner plates every night.

    (and thom, i know you hate inflamation… just google “meat and inflamation” and see what comes up… 🙂 I’m curious what you might make of the work of Dr. Neal Barnard and Dr. Michael Gregor.


    1. // Reply

      Same to you, kind soul.


    2. // Reply

      I feel exactly the same as you. I’ve been telling people too there is an animal holocaust going on daily and that slaughterhouses are akin to ISIS. It hurts my soul every day knowing how much they suffer and that humanity doesn’t care.


    3. // Reply

      Its amazing to see people putting all this effort into saving farm animals with all the human suffering going on in the world…An animal holocaust? Species get wiped out in nature everyday without humans. While factory farming has huge problems. The solution is having a small local farm in each neighborhood. And while it may be easy for those of us in the first world to stay healthy without meat, such a diet is simply not possible for most people on earth.


    4. // Reply

      Christophar V Oh please, a city liberal…


  11. // Reply

    what about milk thistle for fatty liver?


  12. // Reply

    I’m seriously thinking of just quitting alcohol all together for 2018. I’m an “all or nothing” kinda bloke and alcohol is the only thing holding me back. I’ve took Turmeric for over a year now and can attest to the benefits.


    1. // Reply

      Brad Bourgeois how do you take it?


    2. // Reply

      Did you end up going dry for 2018? I’m doing dry July but think I’ll keep it up due to high cholesterol. (7.8)


    3. // Reply

      JBL NYC Great movie. *Love* Liam Neeson.


    4. // Reply

      Paul Cornelius I stopped drinking 30 years ago. I was 22. Never look back!


  13. // Reply

    You de”liver” again


    1. // Reply

      This was great, I been tryin to find out about “what does a severe fatty liver mean” for a while now, and I think this has helped. Have you ever come across – Jeyebastian Venlena Blaster – (do a search on google ) ? Ive heard some awesome things about it and my friend got cool success with it.


    2. // Reply

      If you want to learn how to get rid of your fatty liver then visit this website here: HootLiver.xyz


  14. // Reply

    That’s it I’m going on Keto IF diet


    1. // Reply

      FrancinesVlogs keto is a life saver…


    2. // Reply

      Been on it for over 4 months. Down 42lbs and my mood and hunger hormones are balanced. Very even keel now. My immune system is high. Not even a case of the sniffles for the last 4 months even being surrounded by people who are sick. Usually I get sick 2-3 times a year and mostly in the winter and spring months. Not this time. 🙂


    3. // Reply

      FrancinesVlogs too much protein is harmful to the kidneys


  15. // Reply

    Another great herb that works well with turmeric for liver health is milk thistle seed extract. It just so happens to boost glutathione also.


    1. // Reply

      Great tip! Milk Thistle.


  16. // Reply

    Thank you so much Tom! I’ve been an athlete my whole life. I played tennis in college, I have a six pack, I’ve been able to run a 5 minute mile for well over a decade, and in the summers I can run a four minute mile. Yet I had a real scare a while ago when my doctors thought that I had LIVER CANCER because my liver was so fatty. I’ve been drinking coke and eating lots of fast food because I thought “who cares? I have a six pack and I’m in great shape – I can get away with it”. So wrong. I hadn’t even considered the fact that my diet was affecting my organs – nobody ever told me. Not even my doctors. They always said everything looked fine. I’ve now completely quit sugar, I’m on a keto-ish diet (Robb Wolf style so I cycle in and out of ketosis). I’ve also quit drinking alcohol and I’m much more careful with what kinds of food I’m eating.


    1. // Reply

      Al Bundy your a moron if you never knew fast food and coke fucks up your body


  17. // Reply

    Turmeric becomes much more bioavailable with pepper so we should take them together,


  18. // Reply

    I. Had. Fatty. Liver. And. I. Never. Drank. Al chol. In. My. Life. I’ve. Revrerst. It. By. Diet. More. Greens. Less. Sugary. Foods. Also. Green. Tea. And. Dandoline. Tea. Kale. And. Spinich. And. Cabbage. Also


    1. // Reply

      Hi Teresa! I just got diagnosed, my doctor nonchalantly gave me the bad news. Did you calorie restrict and how long did it take for your liver to go back to normal??


    2. // Reply

      Thanks dor the info. Will Lord willing will get there


    3. // Reply

      t eresa muldoon: Did you also have a problem with the period key on your computer?


    4. // Reply

      Thanks! My doc just told me. How long did it take to reverse it?


  19. // Reply

    I had fatty liver 1 and a half year ago was diagnosed with NAFL chirrosis .I blew up with acites .Had to have liters of fluid removed from my abdomen.Had jaundice and finally episodes of encephalopathy . I was hospitalized several times and was thoroughly tested and put on the list for transplant. Three days later I got a call at 4 am . They had a liver. I received the transplant. Upon inspection my liver had cancer in it and I had a huge blood clot in the hepatic artery.After blood transfusions and dialysis and losing a hundred pounds in 6 weeks.I came home. NO CARBS FOR ME AND NO SUGAR. Take it from me . YOU DON’T WANT TO GO THERE!


    1. // Reply

      Wow. You’ve been through a lot!
      Glad you are better.


  20. // Reply

    1. Less/No Alcohol    2. Eat less fruits   3. Boost Glutathione, Eat Eggs, Cabbage   4.Consume turmeric.  No Junk food, No Sugar, Whole foods and fruits. No Cheat days, its all or nothing.

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